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Lobeglitazone Attenuates Airway Inflammation and Mucus Hypersecretion in a Murine Model of Ovalbumin-Induced Asthma

Lobeglitazone (LB) is a novel agonist of peroxisome proliferator-activated receptor (PPAR)-α and γ that was developed as a drug to treat diabetes mellitus. We explored the ameliorative effects of LB on allergic asthma using a murine model of ovalbumin (OVA)-induced asthma. To boost the immune respon...

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Detalles Bibliográficos
Autores principales:	Shin, Na-Rae, Park, Sung-Hyeuk, Ko, Je-Won, Cho, Young-Kwon, Lee, In-Chul, Kim, Jong-Choon, Shin, In-Sik, Kim, Joong-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092601/ https://www.ncbi.nlm.nih.gov/pubmed/30135657 http://dx.doi.org/10.3389/fphar.2018.00906

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