Cargando…

Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells

BACKGROUND: Treatment of spinal cord injury is dependent on neuronal survival, appropriate synaptic circuit preservation, and inflammatory environment management. In this sense, mesenchymal stem cell (MSC) therapy is a promising tool that can reduce glial reaction and provide trophic factors to lesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spejo, A. B., Chiarotto, G. B., Ferreira, A. D. F., Gomes, D. A., Ferreira, R. S., Barraviera, B., Oliveira, A. L. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092804/ https://www.ncbi.nlm.nih.gov/pubmed/30107848 http://dx.doi.org/10.1186/s12974-018-1268-4

Ejemplares similares

Neuroprotection and immunomodulation by dimethyl fumarate and a heterologous fibrin biopolymer after ventral root avulsion and reimplantation
por: Kempe, Paula R. G., et al.
Publicado: (2020)

Early alterations in the electrophysiological properties of rat spinal motoneurones following neonatal axotomy
por: Mentis, George Z, et al.
Publicado: (2007)

The Regenerative Potential of Facial Nerve Motoneurons following Chronic Axotomy in Rats
por: Ni, Yusu, et al.
Publicado: (2020)

Synaptic Plasticity on Motoneurons After Axotomy: A Necessary Change in Paradigm
por: Alvarez, Francisco J., et al.
Publicado: (2020)

Spinal motoneuron synaptic plasticity after axotomy in the absence of inducible nitric oxide synthase
por: Emirandetti, Amanda, et al.
Publicado: (2010)

Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice
por: Wainwright, Derek A, et al.
Publicado: (2009)

P75 and phosphorylated c-Jun are differentially regulated in spinal motoneurons following axotomy in rats☆
por: Yuan, Qiuju, et al.
Publicado: (2012)

G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice
por: Henriques, Alexandre, et al.
Publicado: (2010)

Functional Motor Recovery from Motoneuron Axotomy Is Compromised in Mice with Defective Corticospinal Projections
por: Ding, Yuetong, et al.
Publicado: (2014)

Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion
por: Ribeiro, Thiago B., et al.
Publicado: (2015)

CD4+ T cell expression of the IL-10 receptor is necessary for facial motoneuron survival after axotomy
por: Runge, Elizabeth M., et al.
Publicado: (2020)

Synaptic plasticity and sensory-motor improvement following fibrin sealant dorsal root reimplantation and mononuclear cell therapy
por: Benitez, Suzana U., et al.
Publicado: (2014)

The Extent of Synaptic Stripping of Motoneurons after Axotomy Is Not Correlated to Activation of Surrounding Glia or Downregulation of Postsynaptic Adhesion Molecules
por: Berg, Alexander, et al.
Publicado: (2013)

Valproic Acid Reduces Neuroinflammation to Provide Retinal Ganglion Cell Neuroprotection in the Retina Axotomy Model
por: Tribble, James R., et al.
Publicado: (2022)

Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration
por: Vidigal de Castro, Mateus, et al.
Publicado: (2016)

In vivo Laser Axotomy in C. elegans
por: Byrne, Alexandra B., et al.
Publicado: (2011)

Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy
por: Runge, Elizabeth M., et al.
Publicado: (2022)

Enhanced Immune Response in Immunodeficient Mice Improves Peripheral Nerve Regeneration Following Axotomy
por: Bombeiro, André L., et al.
Publicado: (2016)

Mesenchymal Stem Cells in a Transgenic Mouse Model of Multiple System Atrophy: Immunomodulation and Neuroprotection
por: Stemberger, Sylvia, et al.
Publicado: (2011)

Intrinsic response of thoracic propriospinal neurons to axotomy
por: Siebert, Justin R, et al.
Publicado: (2010)

Influence of Delivery Method on Neuroprotection by Bone Marrow Mononuclear Cell Therapy following Ventral Root Reimplantation with Fibrin Sealant
por: Barbizan, Roberta, et al.
Publicado: (2014)

Co-transplantation of bone marrow mesenchymal stem cells and monocytes in the brain stem to repair the facial nerve axotomy
por: Wu, Li, et al.
Publicado: (2020)

Neuroprotective Effects of Curcumin-Loaded Emulsomes in a Laser Axotomy-Induced CNS Injury Model
por: Yilmaz, Elif Nur, et al.
Publicado: (2020)

Mesenchymal stem cells and immunomodulation: current status and future prospects
por: Gao, F, et al.
Publicado: (2016)

Cellular and molecular mechanisms involved in the neuroprotective effects of VEGF on motoneurons
por: Lladó, Jerònia, et al.
Publicado: (2013)

Multiple uses of fibrin sealant for nervous system treatment following injury and disease
por: Biscola, Natalia Perussi, et al.
Publicado: (2017)

Calcium in Neuronal and Glial Response to Axotomy
por: Khaitin, Andrey
Publicado: (2021)

Long‐term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS
por: Goutman, Stephen A., et al.
Publicado: (2018)

Effects of dimethyl fumarate on neuroprotection and immunomodulation
por: Albrecht, Philipp, et al.
Publicado: (2012)

New perspectives of immunomodulation and neuroprotection in glaucoma
por: Skopiński, Piotr, et al.
Publicado: (2021)

A new fibrin sealant as a three-dimensional scaffold candidate for mesenchymal stem cells
por: Gasparotto, Vinícius P O, et al.
Publicado: (2014)

Intraspinal Cocainisation
Publicado: (1904)

Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis
por: Lin, Tzuhua, et al.
Publicado: (2017)

Neuroprotective Effect of Vascular Endothelial Growth Factor on Motoneurons of the Oculomotor System
por: Silva-Hucha, Silvia, et al.
Publicado: (2021)

Intraspinal Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis: Phase 1 Trial Outcomes
por: Feldman, Eva L, et al.
Publicado: (2014)

Impairment of toll-like receptors 2 and 4 leads to compensatory mechanisms after sciatic nerve axotomy
por: Freria, C. M., et al.
Publicado: (2016)

Therapeutic Application of Mesenchymal Stem Cells Derived Extracellular Vesicles for Immunomodulation
por: Gomzikova, Marina O., et al.
Publicado: (2019)

Unraveling Axon Guidance during Axotomy and Regeneration
por: Domínguez-Romero, Miguel E., et al.
Publicado: (2021)

Immunomodulation as a neuroprotective strategy after spinal cord injury
por: Monteiro, Susana, et al.
Publicado: (2018)

Roles of Mesenchymal Stem Cells in Tissue Regeneration and Immunomodulation
por: Ayala-Cuellar, Ana Patricia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0qccmm4jah71ec8gvij8ha22ep