Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells

BACKGROUND: Irradiation-induced kidney damage is inevitable during radiotherapeutic practice, which limits effective radiotherapy doses on tumor treatment. In the present study, the role of mTOR complex 1 (mTORC1) signaling was investigated in irradiation-induced renal injuries. METHODS: Mice were e...

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Detalles Bibliográficos
Autores principales: Shao, Lijian, Yang, Wuping, Xu, Rui, Zhu, Shuqin, Huang, Yanqiu, Li, Huan, Wu, Xincheng, Yue, Mengzhen, Xiong, Xiaoliang, Chen, Xiaowen, Kuang, Bohai, Fan, Guangqin, Zhu, Qingxian, Zeng, Huihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092808/
https://www.ncbi.nlm.nih.gov/pubmed/30107854
http://dx.doi.org/10.1186/s13287-018-0963-5

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