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MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME

The gap in knowledge of the molecular mechanisms underlying differentiation of human pluripotent stem cells (hPSCs) into the mesenchymal cell lineages hinders the application of hPSCs for cell-based therapy. In this study, we identified a critical role of muscle segment homeobox 2 (MSX2) in initiati...

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Detalles Bibliográficos
Autores principales: Zhang, Leisheng, Wang, Hongtao, Liu, Cuicui, Wu, Qingqing, Su, Pei, Wu, Dan, Guo, Jiaojiao, Zhou, Wen, Xu, Yuanfu, Shi, Lihong, Zhou, Jiaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092836/
https://www.ncbi.nlm.nih.gov/pubmed/30033084
http://dx.doi.org/10.1016/j.stemcr.2018.06.019

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