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Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets

Interactive and integrative data visualization tools and libraries are integral to exploration and analysis of genomic data. Web based genome browsers allow integrative data exploration of a large number of data sets for a specific region in the genome. Currently available web-based genome browsers...

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Detalles Bibliográficos
Autores principales: Kancherla, Jayaram, Zhang, Alexander, Gottfried, Brian, Bravo, Hector Corrada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092909/
https://www.ncbi.nlm.nih.gov/pubmed/30135734
http://dx.doi.org/10.12688/f1000research.15433.1
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author Kancherla, Jayaram
Zhang, Alexander
Gottfried, Brian
Bravo, Hector Corrada
author_facet Kancherla, Jayaram
Zhang, Alexander
Gottfried, Brian
Bravo, Hector Corrada
author_sort Kancherla, Jayaram
collection PubMed
description Interactive and integrative data visualization tools and libraries are integral to exploration and analysis of genomic data. Web based genome browsers allow integrative data exploration of a large number of data sets for a specific region in the genome. Currently available web-based genome browsers are developed for specific use cases and datasets, therefore integration and extensibility of the visualizations and the underlying libraries from these tools is a challenging task. Genomic data visualization and software libraries that enable bioinformatic researchers and developers to implement customized genomic data viewers and data analyses for their application are much needed. Using recent advances in core web platform APIs and technologies including Web Components, we developed the Epiviz Component Library, a reusable and extensible data visualization library and application framework for genomic data. Epiviz Components can be integrated with most JavaScript libraries and frameworks designed for HTML. To demonstrate the ease of integration with other frameworks, we developed an R/Bioconductor epivizrChart package, that provides interactive, shareable and reproducible visualizations of genomic data objects in R, Shiny and also create standalone HTML documents. The component library is modular by design, reusable and natively extensible and therefore simplifies the process of managing and developing bioinformatic applications.
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spelling pubmed-60929092018-08-21 Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets Kancherla, Jayaram Zhang, Alexander Gottfried, Brian Bravo, Hector Corrada F1000Res Software Tool Article Interactive and integrative data visualization tools and libraries are integral to exploration and analysis of genomic data. Web based genome browsers allow integrative data exploration of a large number of data sets for a specific region in the genome. Currently available web-based genome browsers are developed for specific use cases and datasets, therefore integration and extensibility of the visualizations and the underlying libraries from these tools is a challenging task. Genomic data visualization and software libraries that enable bioinformatic researchers and developers to implement customized genomic data viewers and data analyses for their application are much needed. Using recent advances in core web platform APIs and technologies including Web Components, we developed the Epiviz Component Library, a reusable and extensible data visualization library and application framework for genomic data. Epiviz Components can be integrated with most JavaScript libraries and frameworks designed for HTML. To demonstrate the ease of integration with other frameworks, we developed an R/Bioconductor epivizrChart package, that provides interactive, shareable and reproducible visualizations of genomic data objects in R, Shiny and also create standalone HTML documents. The component library is modular by design, reusable and natively extensible and therefore simplifies the process of managing and developing bioinformatic applications. F1000 Research Limited 2018-07-17 /pmc/articles/PMC6092909/ /pubmed/30135734 http://dx.doi.org/10.12688/f1000research.15433.1 Text en Copyright: © 2018 Kancherla J et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software Tool Article
Kancherla, Jayaram
Zhang, Alexander
Gottfried, Brian
Bravo, Hector Corrada
Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title_full Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title_fullStr Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title_full_unstemmed Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title_short Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets
title_sort epiviz web components: reusable and extensible component library to visualize functional genomic datasets
topic Software Tool Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092909/
https://www.ncbi.nlm.nih.gov/pubmed/30135734
http://dx.doi.org/10.12688/f1000research.15433.1
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