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Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016

Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa....

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Autores principales: So, Ray TY, Perera, Ranawaka APM, Oladipo, Jamiu O, Chu, Daniel KW, Kuranga, Sulyman A, Chan, Kin-ho, Lau, Eric HY, Cheng, Samuel MS, Poon, Leo LM, Webby, Richard J, Peiris, Malik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092911/
https://www.ncbi.nlm.nih.gov/pubmed/30107872
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175
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author So, Ray TY
Perera, Ranawaka APM
Oladipo, Jamiu O
Chu, Daniel KW
Kuranga, Sulyman A
Chan, Kin-ho
Lau, Eric HY
Cheng, Samuel MS
Poon, Leo LM
Webby, Richard J
Peiris, Malik
author_facet So, Ray TY
Perera, Ranawaka APM
Oladipo, Jamiu O
Chu, Daniel KW
Kuranga, Sulyman A
Chan, Kin-ho
Lau, Eric HY
Cheng, Samuel MS
Poon, Leo LM
Webby, Richard J
Peiris, Malik
author_sort So, Ray TY
collection PubMed
description Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa. Methods: In an abattoir in Kano, Nigeria, we tested nasal swabs from camels and investigated 261 humans with repeated occupational exposure to camels, many of whom also reported drinking fresh camel milk (n = 138) or urine (n = 94) or using camel urine for medicinal purposes (n = 96). Results: Weekly MERS-CoV RNA detection in January–February 2016 ranged from 0–8.4% of camels sampled. None of the abattoir workers with exposure to camels had evidence of neutralising antibody to MERS-CoV. Conclusion: There is a need for more studies to investigate whether or not zoonotic transmission of MERS-CoV does take place in Africa.
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spelling pubmed-60929112018-08-29 Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 So, Ray TY Perera, Ranawaka APM Oladipo, Jamiu O Chu, Daniel KW Kuranga, Sulyman A Chan, Kin-ho Lau, Eric HY Cheng, Samuel MS Poon, Leo LM Webby, Richard J Peiris, Malik Euro Surveill Research Article Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa. Methods: In an abattoir in Kano, Nigeria, we tested nasal swabs from camels and investigated 261 humans with repeated occupational exposure to camels, many of whom also reported drinking fresh camel milk (n = 138) or urine (n = 94) or using camel urine for medicinal purposes (n = 96). Results: Weekly MERS-CoV RNA detection in January–February 2016 ranged from 0–8.4% of camels sampled. None of the abattoir workers with exposure to camels had evidence of neutralising antibody to MERS-CoV. Conclusion: There is a need for more studies to investigate whether or not zoonotic transmission of MERS-CoV does take place in Africa. European Centre for Disease Prevention and Control (ECDC) 2018-08-09 /pmc/articles/PMC6092911/ /pubmed/30107872 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Research Article
So, Ray TY
Perera, Ranawaka APM
Oladipo, Jamiu O
Chu, Daniel KW
Kuranga, Sulyman A
Chan, Kin-ho
Lau, Eric HY
Cheng, Samuel MS
Poon, Leo LM
Webby, Richard J
Peiris, Malik
Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title_full Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title_fullStr Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title_full_unstemmed Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title_short Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
title_sort lack of serological evidence of middle east respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in nigeria, 2016
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092911/
https://www.ncbi.nlm.nih.gov/pubmed/30107872
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175
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