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Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092911/ https://www.ncbi.nlm.nih.gov/pubmed/30107872 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175 |
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author | So, Ray TY Perera, Ranawaka APM Oladipo, Jamiu O Chu, Daniel KW Kuranga, Sulyman A Chan, Kin-ho Lau, Eric HY Cheng, Samuel MS Poon, Leo LM Webby, Richard J Peiris, Malik |
author_facet | So, Ray TY Perera, Ranawaka APM Oladipo, Jamiu O Chu, Daniel KW Kuranga, Sulyman A Chan, Kin-ho Lau, Eric HY Cheng, Samuel MS Poon, Leo LM Webby, Richard J Peiris, Malik |
author_sort | So, Ray TY |
collection | PubMed |
description | Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa. Methods: In an abattoir in Kano, Nigeria, we tested nasal swabs from camels and investigated 261 humans with repeated occupational exposure to camels, many of whom also reported drinking fresh camel milk (n = 138) or urine (n = 94) or using camel urine for medicinal purposes (n = 96). Results: Weekly MERS-CoV RNA detection in January–February 2016 ranged from 0–8.4% of camels sampled. None of the abattoir workers with exposure to camels had evidence of neutralising antibody to MERS-CoV. Conclusion: There is a need for more studies to investigate whether or not zoonotic transmission of MERS-CoV does take place in Africa. |
format | Online Article Text |
id | pubmed-6092911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-60929112018-08-29 Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 So, Ray TY Perera, Ranawaka APM Oladipo, Jamiu O Chu, Daniel KW Kuranga, Sulyman A Chan, Kin-ho Lau, Eric HY Cheng, Samuel MS Poon, Leo LM Webby, Richard J Peiris, Malik Euro Surveill Research Article Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic threat of global public health concern and dromedary camels are the source of zoonotic infection. Although MERS-CoV is enzootic in dromedaries in Africa as well as the Middle East, zoonotic disease has not been reported in Africa. Methods: In an abattoir in Kano, Nigeria, we tested nasal swabs from camels and investigated 261 humans with repeated occupational exposure to camels, many of whom also reported drinking fresh camel milk (n = 138) or urine (n = 94) or using camel urine for medicinal purposes (n = 96). Results: Weekly MERS-CoV RNA detection in January–February 2016 ranged from 0–8.4% of camels sampled. None of the abattoir workers with exposure to camels had evidence of neutralising antibody to MERS-CoV. Conclusion: There is a need for more studies to investigate whether or not zoonotic transmission of MERS-CoV does take place in Africa. European Centre for Disease Prevention and Control (ECDC) 2018-08-09 /pmc/articles/PMC6092911/ /pubmed/30107872 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Research Article So, Ray TY Perera, Ranawaka APM Oladipo, Jamiu O Chu, Daniel KW Kuranga, Sulyman A Chan, Kin-ho Lau, Eric HY Cheng, Samuel MS Poon, Leo LM Webby, Richard J Peiris, Malik Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title | Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title_full | Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title_fullStr | Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title_full_unstemmed | Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title_short | Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016 |
title_sort | lack of serological evidence of middle east respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in nigeria, 2016 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092911/ https://www.ncbi.nlm.nih.gov/pubmed/30107872 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.32.1800175 |
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