Luminescent Iridium Complex-Peptide Hybrids (IPHs) for Therapeutics of Cancer: Design and Synthesis of IPHs for Detection of Cancer Cells and Induction of Their Necrosis-Type Cell Death

Death receptors (DR4 and DR5) offer attractive targets for cancer treatment because cancer cell death can be induced by apoptotic signal upon binding of death ligands such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with death receptors. Cyclometalated iridium(III) complexes s...

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Detalles Bibliográficos
Autores principales: Masum, Abdullah-Al, Hisamatsu, Yosuke, Yokoi, Kenta, Aoki, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092981/
https://www.ncbi.nlm.nih.gov/pubmed/30154833
http://dx.doi.org/10.1155/2018/7578965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092981/
https://www.ncbi.nlm.nih.gov/pubmed/30154833
http://dx.doi.org/10.1155/2018/7578965

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