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Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta
Defective placentation is the underlying cause of various pregnancy complications, such as severe intrauterine growth restriction and preeclampsia. However, studies on human placental development are hampered by the lack of a self-renewing in vitro model that would recapitulate formation of trophobl...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092984/ https://www.ncbi.nlm.nih.gov/pubmed/30078556 http://dx.doi.org/10.1016/j.stemcr.2018.07.004 |