Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta

Defective placentation is the underlying cause of various pregnancy complications, such as severe intrauterine growth restriction and preeclampsia. However, studies on human placental development are hampered by the lack of a self-renewing in vitro model that would recapitulate formation of trophobl...

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Detalles Bibliográficos
Autores principales: Haider, Sandra, Meinhardt, Gudrun, Saleh, Leila, Kunihs, Viktoria, Gamperl, Magdalena, Kaindl, Ulrich, Ellinger, Adolf, Burkard, Thomas R., Fiala, Christian, Pollheimer, Jürgen, Mendjan, Sasha, Latos, Paulina A., Knöfler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092984/
https://www.ncbi.nlm.nih.gov/pubmed/30078556
http://dx.doi.org/10.1016/j.stemcr.2018.07.004

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