Cargando…

Inhibiting of GRASP65 Phosphorylation by DL-3-N-Butylphthalide Protects against Cerebral Ischemia-Reperfusion Injury via ERK Signaling

BACKGROUND AND PURPOSE: The aim of this study was to explore the role of DL-3-n-butylphthalide (NBP) in cerebral ischemia-reperfusion injury (CIRI) mice model. The involvement of extracellular signal-regulated kinase (ERK) signaling pathway was also investigated. METHODS: All mice were divided into...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Bei-lei, Xie, Chen-long, Hu, Ning-ning, Zhu, Xin-bo, Liu, Chun-feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093058/ https://www.ncbi.nlm.nih.gov/pubmed/30154935 http://dx.doi.org/10.1155/2018/5701719

Ejemplares similares

Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury
por: Jia, Jingjing, et al.
Publicado: (2023)

Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging
por: Liu, Run-Zhe, et al.
Publicado: (2017)

Dl‐3‐N‐butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats
por: Zhou, Pan‐Ting, et al.
Publicado: (2019)

DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins
por: Ye, Zhan-Ying, et al.
Publicado: (2019)

Protective effects of dl-3n-butylphthalide against diffuse brain injury
por: Zhao, Yaning, et al.
Publicado: (2013)

Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats
por: Sun, Yanan, et al.
Publicado: (2020)

DL-3-n-butylphthalide protects H9c2 cardiomyoblasts from ischemia/reperfusion injury by regulating HSP70 expression via PI3K/AKT pathway activation
por: Yu, Yunchen, et al.
Publicado: (2021)

Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Ameliorates Memory Deficits in Rats with Chronic Cerebral Hypoperfusion
por: Xiong, Zhilin, et al.
Publicado: (2017)

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2019)

Dl-3-n-Butylphthalide (NBP) Mitigates Muscular Injury Induced by Limb Ischemia/Reperfusion in Mice through the HMGB1/TLR4/NF-κB Pathway
por: Sun, Huanhuan, et al.
Publicado: (2022)

Corrigendum: Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2021)

Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats
por: Zhang, Dongqin, et al.
Publicado: (2022)

Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice
por: Yang, Chun-Sheng, et al.
Publicado: (2019)

The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction: A randomized controlled STROBE study
por: Zhang, Chenhao, et al.
Publicado: (2017)

Effects of Dl-3-n-butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Protective Effect of Dl-3n-butylphthalide on Learning and Memory Impairment Induced by Chronic Intermittent Hypoxia-Hypercapnia Exposure
por: Min, Jing-jing, et al.
Publicado: (2014)

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly
por: Tang, Danming, et al.
Publicado: (2012)

dl‐3‐n‐butylphthalide preserves white matter integrity and alleviates cognitive impairment in mice with chronic cerebral hypoperfusion
por: Han, Qin‐Yu, et al.
Publicado: (2019)

DL-3n-Butylphthalide Improves Blood–Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion
por: Mamtilahun, Muyassar, et al.
Publicado: (2021)

Dl-3-n-Butylphthalide Reduced Neuroinflammation by Inhibiting Inflammasome in Microglia in Mice after Middle Cerebral Artery Occlusion
por: Liu, Mengdi, et al.
Publicado: (2022)

Correction to: Effects of Dl-3‑n‑butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Vascular protection and regenerative effects of intranasal DL-3-N-butylphthalide treatment after ischaemic stroke in mice
por: Qu, Mengyao, et al.
Publicado: (2020)

Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway
por: Gao, Yaran, et al.
Publicado: (2022)

3-N-butylphthalide improves neuronal morphology after chronic cerebral ischemia
por: Zhao, Wanhong, et al.
Publicado: (2014)

Impacts of N-Butylphthalide on expression of growth factors in rats with focal cerebral ischemia
por: Jiang, Yan, et al.
Publicado: (2016)

Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice★
por: Wang, Hongbo, et al.
Publicado: (2013)

Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis
por: Xu, Jingyu, et al.
Publicado: (2021)

ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65
por: Bisel, Blaine, et al.
Publicado: (2008)

Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance
por: Song, Kangping, et al.
Publicado: (2022)

DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson’s disease
por: Hu, Chun-Bo, et al.
Publicado: (2022)

GRASP65 gets the chop
por: Wells, William A.
Publicado: (2002)

Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage
por: Tu, Ewen, et al.
Publicado: (2020)

DL-3-n-butylphthalide Increases Collateriogenesis and Functional Recovery after Focal Ischemic Stroke in Mice
por: Wei, Zheng Zachory, et al.
Publicado: (2021)

DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study
por: Chen, Dawei, et al.
Publicado: (2020)

Protective effect of ginkgo proanthocyanidins against cerebral ischemia/reperfusion injury associated with its antioxidant effects
por: Cao, Wang-li, et al.
Publicado: (2016)

Dl-3-n-Butylphthalide Alleviates Hippocampal Neuron Damage in Chronic Cerebral Hypoperfusion via Regulation of the CNTF/CNTFRα/JAK2/STAT3 Signaling Pathways
por: Li, Wenxian, et al.
Publicado: (2021)

DL-3-n-butylphthalide improved physical and learning and memory performance of rodents exposed to acute and chronic hypobaric hypoxia
por: Xu, Gang, et al.
Publicado: (2021)

TREM2 protects against cerebral ischemia/reperfusion injury
por: Wu, Rong, et al.
Publicado: (2017)

Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by ferroptosis regulation via the SLC7A11/GSH/GPX4 pathway and the attenuation of blood–brain barrier disruption
por: Xu, Shuangli, et al.
Publicado: (2023)

Effects of dl‐3‐n‐butylphthalide on serum lipoprotein‐associated phospholipase A2 and hypersensitive C‐reactive protein levels in acute cerebral infarction
por: Zhang, Xiao‐Lei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oaqdmf9jkinc5jb2aid2bsk0t1