The AMPK/p27(Kip1) Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells

Skeletal muscle stem cell (MuSC) function declines with age and contributes to impaired muscle regeneration in older individuals. Acting through AMPK/p27(Kip1), we have identified a pathway regulating the balance between autophagy, apoptosis, and senescence in aged MuSCs. While p27(Kip1) is implicat...

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Detalles Bibliográficos
Autores principales: White, James P., Billin, Andrew N., Campbell, Milton E., Russell, Alan J., Huffman, Kim M., Kraus, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093087/
https://www.ncbi.nlm.nih.gov/pubmed/30033086
http://dx.doi.org/10.1016/j.stemcr.2018.06.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093087/
https://www.ncbi.nlm.nih.gov/pubmed/30033086
http://dx.doi.org/10.1016/j.stemcr.2018.06.014

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