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ADAM10-Initiated Release of Notch Intracellular Domain Regulates Microtubule Stability and Radial Migration of Cortical Neurons

Proper neuronal migration is orchestrated by combined membrane signal paradigms, whereas the role and mechanism of regulated intramembrane proteolysis (RIP) remain to be illustrated. We show here that the disintegrin and metalloprotease-domain containing protein 10 (ADAM10) regulates cortical neuron...

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Detalles Bibliográficos
Autores principales: Yang, Zhi, Li, Peng-Fei, Chen, Ren-Chao, Wang, Jie, Wang, Shaoran, Shen, Ya, Wu, Xiaohui, Fang, Bing, Cheng, Xuewen, Xiong, Zhi-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093323/
https://www.ncbi.nlm.nih.gov/pubmed/28158408
http://dx.doi.org/10.1093/cercor/bhx006