Application of an agr-Specific Antivirulence Compound as Therapy for Staphylococcus aureus-Induced Inflammatory Skin Disease

Atopic dermatitis (AD) is a chronic inflammatory skin disease where more than 90% of patients affected are colonized with Staphylococcus aureus. In AD, S. aureus δ-toxin is a major virulence factor causing cutaneous inflammation via mast cell degranulation. δ-toxin is controlled by the S. aureus agr...

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Detalles Bibliográficos
Autores principales: Baldry, Mara, Nakamura, Yuumi, Nakagawa, Seitaro, Frees, Dorte, Matsue, Hiroyuki, Núñez, Gabriel, Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093339/
https://www.ncbi.nlm.nih.gov/pubmed/29733353
http://dx.doi.org/10.1093/infdis/jiy259

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