Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

Ferroptosis is a form of programmed cell death associated with inflammation, neurodegeneration, and ischemia. Vitamin E (alpha-tocopherol) has been reported to prevent ferroptosis, but the mechanism by which this occurs is controversial. To elucidate the biochemical mechanism of vitamin E activity,...

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Detalles Bibliográficos
Autores principales: Hinman, Andrew, Holst, Charles R., Latham, Joey C., Bruegger, Joel J., Ulas, Gözde, McCusker, Kevin P., Amagata, Akiko, Davis, Dana, Hoff, Kevin G., Kahn-Kirby, Amanda H., Kim, Virna, Kosaka, Yuko, Lee, Edgar, Malone, Stephanie A., Mei, Janet J., Richards, Steve James, Rivera, Veronica, Miller, Guy, Trimmer, Jeffrey K., Shrader, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093661/
https://www.ncbi.nlm.nih.gov/pubmed/30110365
http://dx.doi.org/10.1371/journal.pone.0201369

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