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Inhibition of murine herpesvirus-68 replication by IFN-gamma in macrophages is counteracted by the induction of SOCS1 expression
Gamma interferon (IFN-γ) is known to negatively regulate murine gammaherpesvirus-68 (MHV-68 or γHV-68) replication. This process involves the suppression of the viral gene replication and transcription activator (RTA) promoter, as well as activation of signal transducers and activators of transcript...
Autores principales: | Shen, Yong, Wang, Saisai, Sun, Fangfang, Zheng, Gang, Wu, Tingting, Du, Yushen, Zhang, Suzhan, Qian, Jing, Sun, Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093694/ https://www.ncbi.nlm.nih.gov/pubmed/30075008 http://dx.doi.org/10.1371/journal.ppat.1007202 |
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