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The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution

Membrane proteins are difficult to work with due to their insolubility in aqueous solution and quite often their poor stability in detergent micelles. Here, we present the peptidisc for their facile capture into water-soluble particles. Unlike the nanodisc, which requires scaffold proteins of differ...

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Detalles Bibliográficos
Autores principales: Carlson, Michael Luke, Young, John William, Zhao, Zhiyu, Fabre, Lucien, Jun, Daniel, Li, Jianing, Li, Jun, Dhupar, Harveer Singh, Wason, Irvin, Mills, Allan T, Beatty, J Thomas, Klassen, John S, Rouiller, Isabelle, Duong, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093710/
https://www.ncbi.nlm.nih.gov/pubmed/30109849
http://dx.doi.org/10.7554/eLife.34085