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The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution
Membrane proteins are difficult to work with due to their insolubility in aqueous solution and quite often their poor stability in detergent micelles. Here, we present the peptidisc for their facile capture into water-soluble particles. Unlike the nanodisc, which requires scaffold proteins of differ...
Autores principales: | Carlson, Michael Luke, Young, John William, Zhao, Zhiyu, Fabre, Lucien, Jun, Daniel, Li, Jianing, Li, Jun, Dhupar, Harveer Singh, Wason, Irvin, Mills, Allan T, Beatty, J Thomas, Klassen, John S, Rouiller, Isabelle, Duong, Franck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093710/ https://www.ncbi.nlm.nih.gov/pubmed/30109849 http://dx.doi.org/10.7554/eLife.34085 |
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