Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

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BACKGROUND: Pre-clinical animal studies precede the majority of clinical trials. While the clinical definitions of sepsis and recommended treatments are regularly updated, a systematic review of pre-clinical models of sepsis has not been done and clear modeling guidelines are lacking. OBJECTIVE: To...

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Detalles Bibliográficos
Autores principales: Osuchowski, Marcin F., Ayala, Alfred, Bahrami, Soheyl, Bauer, Michael, Boros, Mihaly, Cavaillon, Jean-Marc, Chaudry, Irshad H., Coopersmith, Craig M., Deutschman, Clifford, Drechsler, Susanne, Efron, Philip, Frostell, Claes, Fritsch, Gerhard, Gozdzik, Waldemar, Hellman, Judith, Huber-Lang, Markus, Inoue, Shigeaki, Knapp, Sylvia, Kozlov, Andrey V., Libert, Claude, Marshall, John C., Moldawer, Lyle L., Radermacher, Peter, Redl, Heinz, Remick, Daniel G., Singer, Mervyn, Thiemermann, Christoph, Wang, Ping, Wiersinga, Willem Joost, Xiao, Xianzhong, Zingarelli, Basilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093828/
https://www.ncbi.nlm.nih.gov/pubmed/30112605
http://dx.doi.org/10.1186/s40635-018-0189-y
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