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Monoclonal antibodies from a patient with anti‐NMDA receptor encephalitis

OBJECTIVE: Anti‐NMDA receptor encephalitis (ANRE) is a potentially lethal encephalitis attributed to autoantibodies against the N‐methyl‐D‐aspartate receptor (NMDAR). We sought to clone and characterize monoclonal antibodies (mAbs) from an ANRE patient. METHODS: We used a hybridoma method to clone t...

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Detalles Bibliográficos
Autores principales: Sharma, Rashmi, Al‐Saleem, Fetweh H., Panzer, Jessica, Lee, Jiwon, Puligedda, Rama Devudu, Felicori, Liza F., Kattala, Chandana Devi, Rattelle, Amy J., Ippolito, Gregory, Cox, Robert H., Lynch, David R., Dessain, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093837/
https://www.ncbi.nlm.nih.gov/pubmed/30128318
http://dx.doi.org/10.1002/acn3.592