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Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy
Deletion of Mapt, encoding the microtubule‐binding protein Tau, prevents disease in multiple genetic models of hyperexcitability. To investigate whether the effect of Tau depletion is generalizable across multiple sodium channel gene‐linked models of epilepsy, we examined the Scn1b (−/−) mouse model...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093838/ https://www.ncbi.nlm.nih.gov/pubmed/30128323 http://dx.doi.org/10.1002/acn3.599 |