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Tethered multifluorophore motion reveals equilibrium transition kinetics of single DNA double helices
We describe a tethered multifluorophore motion assay based on DNA origami for revealing bimolecular reaction kinetics on the single-molecule level. Molecular binding partners may be placed at user-defined positions and in user-defined stoichiometry; and binding states are read out by tracking the mo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094131/ https://www.ncbi.nlm.nih.gov/pubmed/30037988 http://dx.doi.org/10.1073/pnas.1800585115 |