A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release

Enterochromaffin (EC) cells constitute the largest population of intestinal epithelial enteroendocrine (EE) cells. EC cells are proposed to be specialized mechanosensory cells that release serotonin in response to epithelial forces, and thereby regulate intestinal fluid secretion. However, it is unk...

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Detalles Bibliográficos
Autores principales: Alcaino, Constanza, Knutson, Kaitlyn R., Treichel, Anthony J., Yildiz, Gulcan, Strege, Peter R., Linden, David R., Li, Joyce H., Leiter, Andrew B., Szurszewski, Joseph H., Farrugia, Gianrico, Beyder, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094143/
https://www.ncbi.nlm.nih.gov/pubmed/30037999
http://dx.doi.org/10.1073/pnas.1804938115

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