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An Improved Inactivated Influenza Vaccine with Enhanced Cross Protection

Current inactivated influenza vaccines are strain-specific and poorly effective against variant or mismatched viruses. They are standardized based on their hemagglutinin (HA) or ability to induce strain-specific hemagglutination inhibition (HAI) antibodies. The HA is known to undergo major conformat...

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Detalles Bibliográficos
Autores principales: Ni, Yawei, Guo, Jianhua, Turner, Debra, Tizard, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094167/
https://www.ncbi.nlm.nih.gov/pubmed/30140267
http://dx.doi.org/10.3389/fimmu.2018.01815