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Synthesis of Linear and Cyclic Disulfide Heptapeptides of Longicalycinin A and Evaluation of Toxicity on Cancerous Cells HepG2 and HT-29

In this work, linear and cyclic disulfide heptapeptides of Longicalycinin A have been successfully synthesized by solid phase methodology with Fmoc /t-Bu and solution phase, respectively. 2-Chlorotrityl chloride resin (2-CTC) was used as a solid support. The synthesized linear disulfide analogue of...

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Detalles Bibliográficos
Autores principales: HoushdarTehrani, Mohammad Hassan, Bamoniri, Abdolhamid, Mirjalili, Bi Bi Fatemeh, Gholibeikian, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094423/
https://www.ncbi.nlm.nih.gov/pubmed/30127818