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Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup

BACKGROUND: Reliable biomarkers of frontotemporal dementia (FTD) are currently lacking. FTD may be associated with chronic immune dysfunction, microglial activation and raised inflammatory markers, particularly in progranulin (GRN) mutation carriers. Levels of soluble triggering receptor expressed o...

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Detalles Bibliográficos
Autores principales:	Woollacott, Ione O. C., Nicholas, Jennifer M., Heslegrave, Amanda, Heller, Carolin, Foiani, Martha S., Dick, Katrina M., Russell, Lucy L., Paterson, Ross W., Keshavan, Ashvini, Fox, Nick C., Warren, Jason D., Schott, Jonathan M., Zetterberg, Henrik, Rohrer, Jonathan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094471/ https://www.ncbi.nlm.nih.gov/pubmed/30111356 http://dx.doi.org/10.1186/s13195-018-0405-8

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