Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

BACKGROUND: Murine breast cancer models relying on intraductal tumor cell inoculations are attractive because they allow the study of breast cancer from early ductal carcinoma in situ to metastasis. Using a fully immunocompetent 4T1-based intraductal model for triple-negative breast cancer (TNBC) we...

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Detalles Bibliográficos
Autores principales: Steenbrugge, Jonas, Breyne, Koen, Demeyere, Kristel, De Wever, Olivier, Sanders, Niek N., Van Den Broeck, Wim, Colpaert, Cecile, Vermeulen, Peter, Van Laere, Steven, Meyer, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094904/
https://www.ncbi.nlm.nih.gov/pubmed/30111338
http://dx.doi.org/10.1186/s13046-018-0860-x

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