Triptolide inhibits Epstein-Barr nuclear antigen 1 expression by increasing sensitivity of mitochondria apoptosis of nasopharyngeal carcinoma cells

BACKGROUND: Epstein-Barr virus (EBV) is widely found in nasopharyngeal carcinoma (NPC) tissue and associated with poor prognosis of patients. EBV nuclear antigen 1 (EBNA1) is expressed in all NPC tumors and plays multiple biological roles in both virus and host cells. Triptolide is a natural product...

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Detalles Bibliográficos
Autores principales: Zhou, Heng, Liu, Yu, Wang, Chao, Liu, Limei, Wang, Huan, Zhang, Yaqian, Long, Cong, Sun, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094928/
https://www.ncbi.nlm.nih.gov/pubmed/30111354
http://dx.doi.org/10.1186/s13046-018-0865-5

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