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Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer’s Disease

The mechanistic target of rapamycin (mTOR) is a nutrient sensor of eukaryotic cells. Inhibition of mechanistic mTOR signaling can increase life and health span in various species via interventions that include rapamycin and caloric restriction (CR). In the central nervous system, mTOR inhibition dem...

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Detalles Bibliográficos
Autores principales:	Lee, Jennifer, Yanckello, Lucille M., Ma, David, Hoffman, Jared D., Parikh, Ishita, Thalman, Scott, Bauer, Bjoern, Hartz, Anika M. S., Hyder, Fahmeed, Lin, Ai-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094969/ https://www.ncbi.nlm.nih.gov/pubmed/30140223 http://dx.doi.org/10.3389/fnagi.2018.00225

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