Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging

Transcranial direct-current stimulation (DCS) offers a method for noninvasive neuromodulation usable in basic and clinical human neuroscience. Laser-speckle contrast imaging (LSCI), a powerful, low-cost method for obtaining images of dynamic systems, can detect regional blood-flow distributions with...

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Detalles Bibliográficos
Autores principales: Hu, Shuo, Zheng, Tao, Dong, Yanchao, Du, Juan, Liu, Lanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094971/
https://www.ncbi.nlm.nih.gov/pubmed/30140201
http://dx.doi.org/10.3389/fnins.2018.00503
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author Hu, Shuo
Zheng, Tao
Dong, Yanchao
Du, Juan
Liu, Lanxiang
author_facet Hu, Shuo
Zheng, Tao
Dong, Yanchao
Du, Juan
Liu, Lanxiang
author_sort Hu, Shuo
collection PubMed
description Transcranial direct-current stimulation (DCS) offers a method for noninvasive neuromodulation usable in basic and clinical human neuroscience. Laser-speckle contrast imaging (LSCI), a powerful, low-cost method for obtaining images of dynamic systems, can detect regional blood-flow distributions with high spatial and temporal resolutions. Here, we used LSCI for measuring DCS-induced cerebral blood flow in real-time. Results showed that the change-rate of cerebral blood flow could reach approximately 10.1 ± 5.1% by DCS, indicating that DCS can increase cerebral blood flow and alter cortical hemodynamic responses. Thus, DCS shows potential for the clinical treatment and rehabilitation of ischemic strokes.
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spelling pubmed-60949712018-08-23 Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging Hu, Shuo Zheng, Tao Dong, Yanchao Du, Juan Liu, Lanxiang Front Neurosci Neuroscience Transcranial direct-current stimulation (DCS) offers a method for noninvasive neuromodulation usable in basic and clinical human neuroscience. Laser-speckle contrast imaging (LSCI), a powerful, low-cost method for obtaining images of dynamic systems, can detect regional blood-flow distributions with high spatial and temporal resolutions. Here, we used LSCI for measuring DCS-induced cerebral blood flow in real-time. Results showed that the change-rate of cerebral blood flow could reach approximately 10.1 ± 5.1% by DCS, indicating that DCS can increase cerebral blood flow and alter cortical hemodynamic responses. Thus, DCS shows potential for the clinical treatment and rehabilitation of ischemic strokes. Frontiers Media S.A. 2018-07-26 /pmc/articles/PMC6094971/ /pubmed/30140201 http://dx.doi.org/10.3389/fnins.2018.00503 Text en Copyright © 2018 Hu, Zheng, Dong, Du and Liu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Hu, Shuo
Zheng, Tao
Dong, Yanchao
Du, Juan
Liu, Lanxiang
Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title_full Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title_fullStr Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title_full_unstemmed Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title_short Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
title_sort effect of anodal direct-current stimulation on cortical hemodynamic responses with laser-speckle contrast imaging
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094971/
https://www.ncbi.nlm.nih.gov/pubmed/30140201
http://dx.doi.org/10.3389/fnins.2018.00503
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