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The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation

The mouse superior colliculus (SC) is a laminar midbrain structure involved in processing and transforming multimodal sensory stimuli into ethologically relevant behaviors such as escape, defense, and orienting movements. The SC is unique in that the sensory (visual, auditory, and somatosensory) and...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana F., Yonehara, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094993/
https://www.ncbi.nlm.nih.gov/pubmed/30140205
http://dx.doi.org/10.3389/fncir.2018.00059
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author Oliveira, Ana F.
Yonehara, Keisuke
author_facet Oliveira, Ana F.
Yonehara, Keisuke
author_sort Oliveira, Ana F.
collection PubMed
description The mouse superior colliculus (SC) is a laminar midbrain structure involved in processing and transforming multimodal sensory stimuli into ethologically relevant behaviors such as escape, defense, and orienting movements. The SC is unique in that the sensory (visual, auditory, and somatosensory) and motor maps are overlaid. In the mouse, the SC receives inputs from more retinal ganglion cells than any other visual area. This makes the mouse SC an ideal model system for understanding how visual signals processed by retinal circuits are used to mediate visually guided behaviors. This Perspective provides an overview of the current understanding of visual motor transformations operated by the mouse SC and discusses the challenges to be overcome when investigating the input–output relationships in single collicular cell types.
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spelling pubmed-60949932018-08-23 The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation Oliveira, Ana F. Yonehara, Keisuke Front Neural Circuits Neuroscience The mouse superior colliculus (SC) is a laminar midbrain structure involved in processing and transforming multimodal sensory stimuli into ethologically relevant behaviors such as escape, defense, and orienting movements. The SC is unique in that the sensory (visual, auditory, and somatosensory) and motor maps are overlaid. In the mouse, the SC receives inputs from more retinal ganglion cells than any other visual area. This makes the mouse SC an ideal model system for understanding how visual signals processed by retinal circuits are used to mediate visually guided behaviors. This Perspective provides an overview of the current understanding of visual motor transformations operated by the mouse SC and discusses the challenges to be overcome when investigating the input–output relationships in single collicular cell types. Frontiers Media S.A. 2018-07-24 /pmc/articles/PMC6094993/ /pubmed/30140205 http://dx.doi.org/10.3389/fncir.2018.00059 Text en Copyright © 2018 Oliveira and Yonehara. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Oliveira, Ana F.
Yonehara, Keisuke
The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title_full The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title_fullStr The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title_full_unstemmed The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title_short The Mouse Superior Colliculus as a Model System for Investigating Cell Type-Based Mechanisms of Visual Motor Transformation
title_sort mouse superior colliculus as a model system for investigating cell type-based mechanisms of visual motor transformation
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094993/
https://www.ncbi.nlm.nih.gov/pubmed/30140205
http://dx.doi.org/10.3389/fncir.2018.00059
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