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Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections
By using AT8-immunocytochemistry that visualizes hyperphosphorylated tau protein, we examined neurofibrillary changes related to sporadic Alzheimer’s disease (AD) in N = 40 individuals at neurofibrillary tangle (NFT) stages I–IV. We report the presence of abnormal tau changes within solitary pyramid...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095209/ https://www.ncbi.nlm.nih.gov/pubmed/29982389 http://dx.doi.org/10.1093/cercor/bhy152 |