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Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study

Interactions with the environment happen within one’s peripersonal space (PPS)—the space surrounding the body. Studies in monkeys and humans have highlighted a multisensory distributed cortical network representing the PPS. However, knowledge about the temporal dynamics of PPS processing around the...

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Autores principales: Bernasconi, Fosco, Noel, Jean-Paul, Park, Hyeong Dong, Faivre, Nathan, Seeck, Margitta, Spinelli, Laurent, Schaller, Karl, Blanke, Olaf, Serino, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095214/
https://www.ncbi.nlm.nih.gov/pubmed/30010843
http://dx.doi.org/10.1093/cercor/bhy156
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author Bernasconi, Fosco
Noel, Jean-Paul
Park, Hyeong Dong
Faivre, Nathan
Seeck, Margitta
Spinelli, Laurent
Schaller, Karl
Blanke, Olaf
Serino, Andrea
author_facet Bernasconi, Fosco
Noel, Jean-Paul
Park, Hyeong Dong
Faivre, Nathan
Seeck, Margitta
Spinelli, Laurent
Schaller, Karl
Blanke, Olaf
Serino, Andrea
author_sort Bernasconi, Fosco
collection PubMed
description Interactions with the environment happen within one’s peripersonal space (PPS)—the space surrounding the body. Studies in monkeys and humans have highlighted a multisensory distributed cortical network representing the PPS. However, knowledge about the temporal dynamics of PPS processing around the trunk is lacking. Here, we recorded intracranial electroencephalography (iEEG) in humans while administering tactile stimulation (T), approaching auditory stimuli (A), and the 2 combined (AT). To map PPS, tactile stimulation was delivered when the sound was far, intermediate, or close to the body. The 19% of the electrodes showed AT multisensory integration. Among those, 30% showed a PPS effect, a modulation of the response as a function of the distance between the sound and body. AT multisensory integration and PPS effects had similar spatiotemporal characteristics, with an early response (~50 ms) in the insular cortex, and later responses (~200 ms) in precentral and postcentral gyri. Superior temporal cortex showed a different response pattern with AT multisensory integration at ~100 ms without a PPS effect. These results, represent the first iEEG delineation of PPS processing in humans and show that PPS and multisensory integration happen at similar neural sites and time periods, suggesting that PPS representation is based on a spatial modulation of multisensory integration.
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spelling pubmed-60952142018-08-22 Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study Bernasconi, Fosco Noel, Jean-Paul Park, Hyeong Dong Faivre, Nathan Seeck, Margitta Spinelli, Laurent Schaller, Karl Blanke, Olaf Serino, Andrea Cereb Cortex Original Articles Interactions with the environment happen within one’s peripersonal space (PPS)—the space surrounding the body. Studies in monkeys and humans have highlighted a multisensory distributed cortical network representing the PPS. However, knowledge about the temporal dynamics of PPS processing around the trunk is lacking. Here, we recorded intracranial electroencephalography (iEEG) in humans while administering tactile stimulation (T), approaching auditory stimuli (A), and the 2 combined (AT). To map PPS, tactile stimulation was delivered when the sound was far, intermediate, or close to the body. The 19% of the electrodes showed AT multisensory integration. Among those, 30% showed a PPS effect, a modulation of the response as a function of the distance between the sound and body. AT multisensory integration and PPS effects had similar spatiotemporal characteristics, with an early response (~50 ms) in the insular cortex, and later responses (~200 ms) in precentral and postcentral gyri. Superior temporal cortex showed a different response pattern with AT multisensory integration at ~100 ms without a PPS effect. These results, represent the first iEEG delineation of PPS processing in humans and show that PPS and multisensory integration happen at similar neural sites and time periods, suggesting that PPS representation is based on a spatial modulation of multisensory integration. Oxford University Press 2018-09 2018-07-12 /pmc/articles/PMC6095214/ /pubmed/30010843 http://dx.doi.org/10.1093/cercor/bhy156 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Articles
Bernasconi, Fosco
Noel, Jean-Paul
Park, Hyeong Dong
Faivre, Nathan
Seeck, Margitta
Spinelli, Laurent
Schaller, Karl
Blanke, Olaf
Serino, Andrea
Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title_full Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title_fullStr Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title_full_unstemmed Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title_short Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
title_sort audio-tactile and peripersonal space processing around the trunk in human parietal and temporal cortex: an intracranial eeg study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095214/
https://www.ncbi.nlm.nih.gov/pubmed/30010843
http://dx.doi.org/10.1093/cercor/bhy156
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