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Strategies for improving the early diagnosis of keratoconus
To diagnose keratoconus at its earliest stage is meaningful in order to avoid refractive surgery in the eye, which may lead to further damage in the abnormal cornea structure and consequently cause iatrogenic ectasia. In this article, the following aspects of detecting earliest stage of keratoconus...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095365/ https://www.ncbi.nlm.nih.gov/pubmed/30214345 http://dx.doi.org/10.2147/OPTO.S63486 |
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author | Shi, Yue |
author_facet | Shi, Yue |
author_sort | Shi, Yue |
collection | PubMed |
description | To diagnose keratoconus at its earliest stage is meaningful in order to avoid refractive surgery in the eye, which may lead to further damage in the abnormal cornea structure and consequently cause iatrogenic ectasia. In this article, the following aspects of detecting earliest stage of keratoconus were reviewed: 1) nomenclature of the earliest forms of keratoconus; 2) diagnosis of keratoconus using curvature-based topography (also known as Placido-based topography, ie, videokeratography) as a traditional method and elevation-based topography as a new method which has gained popularity in recent years; and 3) other methods analyzing keratoconus cornea like corneal biomechanics and wavefront sensing. Elevation-based topography using either Scheimpflug imaging techniques or slit-scanning imaging techniques has shown to be advantageous over the curvature-based topography in detecting keratoconus at its earliest stage. Posterior elevation of the cornea is notified to enhance the sensitivity and specificity of detection if used along with the measurements of anterior surface of the cornea. Cornea biomechanics analysis and wavefront sensing also revealed differences between normal eyes and keratoconic eyes in their earliest stage. Combining the latest technology and the traditional techniques will be the future trend to improve early diagnosis of keratoconus. |
format | Online Article Text |
id | pubmed-6095365 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60953652018-09-13 Strategies for improving the early diagnosis of keratoconus Shi, Yue Clin Optom (Auckl) Review To diagnose keratoconus at its earliest stage is meaningful in order to avoid refractive surgery in the eye, which may lead to further damage in the abnormal cornea structure and consequently cause iatrogenic ectasia. In this article, the following aspects of detecting earliest stage of keratoconus were reviewed: 1) nomenclature of the earliest forms of keratoconus; 2) diagnosis of keratoconus using curvature-based topography (also known as Placido-based topography, ie, videokeratography) as a traditional method and elevation-based topography as a new method which has gained popularity in recent years; and 3) other methods analyzing keratoconus cornea like corneal biomechanics and wavefront sensing. Elevation-based topography using either Scheimpflug imaging techniques or slit-scanning imaging techniques has shown to be advantageous over the curvature-based topography in detecting keratoconus at its earliest stage. Posterior elevation of the cornea is notified to enhance the sensitivity and specificity of detection if used along with the measurements of anterior surface of the cornea. Cornea biomechanics analysis and wavefront sensing also revealed differences between normal eyes and keratoconic eyes in their earliest stage. Combining the latest technology and the traditional techniques will be the future trend to improve early diagnosis of keratoconus. Dove Medical Press 2016-02-24 /pmc/articles/PMC6095365/ /pubmed/30214345 http://dx.doi.org/10.2147/OPTO.S63486 Text en © 2016 Shi. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Shi, Yue Strategies for improving the early diagnosis of keratoconus |
title | Strategies for improving the early diagnosis of keratoconus |
title_full | Strategies for improving the early diagnosis of keratoconus |
title_fullStr | Strategies for improving the early diagnosis of keratoconus |
title_full_unstemmed | Strategies for improving the early diagnosis of keratoconus |
title_short | Strategies for improving the early diagnosis of keratoconus |
title_sort | strategies for improving the early diagnosis of keratoconus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095365/ https://www.ncbi.nlm.nih.gov/pubmed/30214345 http://dx.doi.org/10.2147/OPTO.S63486 |
work_keys_str_mv | AT shiyue strategiesforimprovingtheearlydiagnosisofkeratoconus |