Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis

New effective compounds for tuberculosis treatment are needed. This study evaluated the effects of a series of quinoxaline-derived chalcones against laboratorial strains and clinical isolates of M. tuberculosis. Six molecules, namely N5, N9, N10, N15, N16, and N23 inhibited the growth of the M. tube...

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Detalles Bibliográficos
Autores principales: Muradás, Thaís C., Abbadi, Bruno L., Villela, Anne D., Macchi, Fernanda S., Bergo, Pedro F., de Freitas, Talita F., Sperotto, Nathalia D. M., Timmers, Luis F. S. M., Norberto de Souza, Osmar, Picada, Jaqueline N., Fachini, Jean, da Silva, Juliana Bondan, de Albuquerque, Nayara C. P., Habenschus, Maísa D., Carrão, Daniel B., Rocha, Bruno A., Barbosa Junior, Fernando, de Oliveira, Anderson R. M., Mascarello, Alessandra, Neuenfeldf, Patrícia, Nunes, Ricardo J., Morbidoni, Héctor R., Campos, Maria M., Basso, Luiz A., Rodrigues-Junior, Valnês S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095594/
https://www.ncbi.nlm.nih.gov/pubmed/30114296
http://dx.doi.org/10.1371/journal.pone.0202568

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