UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling

The mTOR signaling pathways regulate cell growth and are involved in multiple human diseases. Here, we identify UBTOR, a previously unannotated gene as a functional player in regulating cell growth and mTOR signaling. Reduction of UBTOR function in cultured hippocampal neurons and PC12 cells promote...

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Detalles Bibliográficos
Autores principales: Zhang, Hefei, Zhang, Quan, Gao, Ge, Wang, Xinjian, Wang, Tiantian, Kong, Zhitao, Wang, Guoxiang, Zhang, Cuizhen, Wang, Yun, Peng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095612/
https://www.ncbi.nlm.nih.gov/pubmed/30080879
http://dx.doi.org/10.1371/journal.pgen.1007583

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