Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

There is need for a more efficient cell-based assay amenable to high-throughput drug screening against Giardia lamblia. Here, we report the development of a screening method utilizing G. lamblia engineered to express red-shifted firefly luciferase. Parasite growth and replication were quantified usi...

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Detalles Bibliográficos
Autores principales: Hennessey, Kelly M., Rogiers, Ilse C., Shih, Han-Wei, Hulverson, Matthew A., Choi, Ryan, McCloskey, Molly C., Whitman, Grant R., Barrett, Lynn K., Merritt, Ethan A., Paredez, Alexander R., Ojo, Kayode K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095626/
https://www.ncbi.nlm.nih.gov/pubmed/30080847
http://dx.doi.org/10.1371/journal.pntd.0006673

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