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Reconstruction of the cell entry pathway of an extinct virus

Endogenous retroviruses (ERVs), remnants of ancient germline infections, comprise 8% of the human genome. The most recently integrated includes human ERV-K (HERV-K) where several envelope (env) sequences remain intact. Viral pseudotypes decorated with one of those Envs are infectious. Using a recomb...

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Detalles Bibliográficos
Autores principales: Robinson-McCarthy, Lindsey R., McCarthy, Kevin R., Raaben, Matthijs, Piccinotti, Silvia, Nieuwenhuis, Joppe, Stubbs, Sarah H., Bakkers, Mark J. G., Whelan, Sean P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095630/
https://www.ncbi.nlm.nih.gov/pubmed/30080900
http://dx.doi.org/10.1371/journal.ppat.1007123