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Hematopoietic reconstitution of neonatal immunocompetent mice to study conditions with a perinatal window of susceptibility
Efficient hematopoietic reconstitution of wild type mice requires preconditioning. Established experimental protocols exist to transplant hematopoietic stem cells into lethally irradiated or chemically myeloablated adult mice or unirradiated immunodeficient mice. We sought to develop a protocol to r...
Autores principales: | Laky, Karen, Dugan, Philip, Frischmeyer-Guerrerio, Pamela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095844/ https://www.ncbi.nlm.nih.gov/pubmed/30115970 http://dx.doi.org/10.1038/s41598-018-30767-1 |
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