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Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression

Hyperglycemia stimulates several pathways to induce pancreatic β-cell apoptosis. In our previous study by mRNA analysis, we demonstrated that B-cell translocation gene 2 (BTG(2)) expression was up-regulated in INS-1 cells cultured under high glucose conditions, but this effect was reversed by estrog...

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Detalles Bibliográficos
Autores principales: Kooptiwut, Suwattanee, Kaewin, Suchada, Semprasert, Namoiy, Sujjitjoon, Jatuporn, Junking, Mutita, Suksri, Kanchana, Yenchitsomanus, Pa-thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095866/
https://www.ncbi.nlm.nih.gov/pubmed/30115961
http://dx.doi.org/10.1038/s41598-018-30698-x