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Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression
Hyperglycemia stimulates several pathways to induce pancreatic β-cell apoptosis. In our previous study by mRNA analysis, we demonstrated that B-cell translocation gene 2 (BTG(2)) expression was up-regulated in INS-1 cells cultured under high glucose conditions, but this effect was reversed by estrog...
Autores principales: | Kooptiwut, Suwattanee, Kaewin, Suchada, Semprasert, Namoiy, Sujjitjoon, Jatuporn, Junking, Mutita, Suksri, Kanchana, Yenchitsomanus, Pa-thai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095866/ https://www.ncbi.nlm.nih.gov/pubmed/30115961 http://dx.doi.org/10.1038/s41598-018-30698-x |
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