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The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome

Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese...

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Autores principales: Ueno, Tatsuya, Kimura, Ryoya, Kon, Tomoya, Haga, Rie, Nishijima, Haruo, Nunomura, Jin-ichi, Tomiyama, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096018/
https://www.ncbi.nlm.nih.gov/pubmed/29491292
http://dx.doi.org/10.2169/internalmedicine.0313-17
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author Ueno, Tatsuya
Kimura, Ryoya
Kon, Tomoya
Haga, Rie
Nishijima, Haruo
Nunomura, Jin-ichi
Tomiyama, Masahiko
author_facet Ueno, Tatsuya
Kimura, Ryoya
Kon, Tomoya
Haga, Rie
Nishijima, Haruo
Nunomura, Jin-ichi
Tomiyama, Masahiko
author_sort Ueno, Tatsuya
collection PubMed
description Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese man who presented only with ataxia symptoms and was positive for the anti-GQ1b antibody. However, the patient also suffered from dysgeusia, a significant impairment of taste perception. We propose that dysgeusia in acute-onset ataxia cases may constitute an important clinical feature to aid in the diagnosis of the incomplete form of MFS.
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spelling pubmed-60960182018-08-17 The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome Ueno, Tatsuya Kimura, Ryoya Kon, Tomoya Haga, Rie Nishijima, Haruo Nunomura, Jin-ichi Tomiyama, Masahiko Intern Med Case Report Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese man who presented only with ataxia symptoms and was positive for the anti-GQ1b antibody. However, the patient also suffered from dysgeusia, a significant impairment of taste perception. We propose that dysgeusia in acute-onset ataxia cases may constitute an important clinical feature to aid in the diagnosis of the incomplete form of MFS. The Japanese Society of Internal Medicine 2018-02-28 2018-07-15 /pmc/articles/PMC6096018/ /pubmed/29491292 http://dx.doi.org/10.2169/internalmedicine.0313-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ueno, Tatsuya
Kimura, Ryoya
Kon, Tomoya
Haga, Rie
Nishijima, Haruo
Nunomura, Jin-ichi
Tomiyama, Masahiko
The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title_full The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title_fullStr The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title_full_unstemmed The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title_short The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
title_sort differential diagnosis of acute onset truncal ataxia: the importance of dysgeusia in miller fisher syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096018/
https://www.ncbi.nlm.nih.gov/pubmed/29491292
http://dx.doi.org/10.2169/internalmedicine.0313-17
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