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The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome
Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Society of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096018/ https://www.ncbi.nlm.nih.gov/pubmed/29491292 http://dx.doi.org/10.2169/internalmedicine.0313-17 |
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author | Ueno, Tatsuya Kimura, Ryoya Kon, Tomoya Haga, Rie Nishijima, Haruo Nunomura, Jin-ichi Tomiyama, Masahiko |
author_facet | Ueno, Tatsuya Kimura, Ryoya Kon, Tomoya Haga, Rie Nishijima, Haruo Nunomura, Jin-ichi Tomiyama, Masahiko |
author_sort | Ueno, Tatsuya |
collection | PubMed |
description | Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese man who presented only with ataxia symptoms and was positive for the anti-GQ1b antibody. However, the patient also suffered from dysgeusia, a significant impairment of taste perception. We propose that dysgeusia in acute-onset ataxia cases may constitute an important clinical feature to aid in the diagnosis of the incomplete form of MFS. |
format | Online Article Text |
id | pubmed-6096018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-60960182018-08-17 The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome Ueno, Tatsuya Kimura, Ryoya Kon, Tomoya Haga, Rie Nishijima, Haruo Nunomura, Jin-ichi Tomiyama, Masahiko Intern Med Case Report Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild cases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese man who presented only with ataxia symptoms and was positive for the anti-GQ1b antibody. However, the patient also suffered from dysgeusia, a significant impairment of taste perception. We propose that dysgeusia in acute-onset ataxia cases may constitute an important clinical feature to aid in the diagnosis of the incomplete form of MFS. The Japanese Society of Internal Medicine 2018-02-28 2018-07-15 /pmc/articles/PMC6096018/ /pubmed/29491292 http://dx.doi.org/10.2169/internalmedicine.0313-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ueno, Tatsuya Kimura, Ryoya Kon, Tomoya Haga, Rie Nishijima, Haruo Nunomura, Jin-ichi Tomiyama, Masahiko The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title | The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title_full | The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title_fullStr | The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title_full_unstemmed | The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title_short | The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome |
title_sort | differential diagnosis of acute onset truncal ataxia: the importance of dysgeusia in miller fisher syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096018/ https://www.ncbi.nlm.nih.gov/pubmed/29491292 http://dx.doi.org/10.2169/internalmedicine.0313-17 |
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