Cargando…

SMOC1 silencing suppresses the angiotensin II-induced myocardial fibrosis of mouse myocardial fibroblasts via affecting the BMP2/Smad pathway

SPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. The present study aimed to investigate the roles and molecular mechanisms of SMOC1 silencing on the fi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yize, Wu, Xianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096163/ https://www.ncbi.nlm.nih.gov/pubmed/30127878 http://dx.doi.org/10.3892/ol.2018.8989

Ejemplares similares

Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway
por: Rui, Huang, et al.
Publicado: (2023)

SMOC can act as both an antagonist and an expander of BMP signaling
por: Thomas, J Terrig, et al.
Publicado: (2017)

C. elegans SMOC-1 interacts with both BMP and glypican to regulate BMP signaling
por: DeGroot, Melisa S., et al.
Publicado: (2023)

SMOC-1 interacts with both BMP and glypican to regulate BMP signaling in C. elegans
por: DeGroot, Melisa S., et al.
Publicado: (2023)

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer
por: Aoki, Hironori, et al.
Publicado: (2017)

Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
por: Xin, Cuiyan, et al.
Publicado: (2021)

Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2
por: Takahata, Yoshifumi, et al.
Publicado: (2021)

Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice
por: Rainger, Joe, et al.
Publicado: (2011)

CircMACF1 alleviates myocardial fibrosis after acute myocardial infarction by suppressing cardiac fibroblast activation via the miR-16-5p/SMAD7 axis
por: Wang, Yonghong, et al.
Publicado: (2023)

Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis
por: Rosin, Nicole L, et al.
Publicado: (2014)

Correction: Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice
por: Rainger, Joe, et al.
Publicado: (2018)

Tranilast inhibits angiotensin II-induced myocardial fibrosis through S100A11/ transforming growth factor-β (TGF-β1)/Smad axis
por: Chen, Youquan, et al.
Publicado: (2021)

Recruitment of macrophages from the spleen contributes to myocardial fibrosis and hypertension induced by angiotensin II
por: Wang, Ning-Ping, et al.
Publicado: (2017)

MOOCs and SMOCs: changing the face of medical education?
por: Sharma, Neel, et al.
Publicado: (2014)

Suppression of TGF-β(1)/Smad Signaling Pathway by Sesamin Contributes to the Attenuation of Myocardial Fibrosis in Spontaneously Hypertensive Rats
por: Zhao, Mengqiu, et al.
Publicado: (2015)

Glycolysis Inhibition Alleviates Cardiac Fibrosis After Myocardial Infarction by Suppressing Cardiac Fibroblast Activation
por: Chen, Zhi-Teng, et al.
Publicado: (2021)

Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II
por: Ma, Feifei, et al.
Publicado: (2012)

Levocarnitine regulates the growth of angiotensin II-induced myocardial fibrosis cells via TIMP-1
por: Shu, Jin, et al.
Publicado: (2023)

BMP6 knockdown enhances cardiac fibrosis in a mouse myocardial infarction model by upregulating AP‐1/CEMIP expression
por: Lu, Guiping, et al.
Publicado: (2023)

The effects of mouse ovarian granulosa cell function and related gene expression by suppressing BMP/Smad signaling pathway
por: Zhang, Li, et al.
Publicado: (2018)

Protective Effects of Sacubitril/Valsartan on Cardiac Fibrosis and Function in Rats With Experimental Myocardial Infarction Involves Inhibition of Collagen Synthesis by Myocardial Fibroblasts Through Downregulating TGF-β1/Smads Pathway
por: Wu, Meifang, et al.
Publicado: (2021)

Calcium-sensing receptor promotes high glucose-induced myocardial fibrosis via upregulation of the TGF-β(1)/Smads pathway in cardiac fibroblasts
por: Yuan, Hui, et al.
Publicado: (2019)

SMOC2 plays a role in heart failure via regulating TGF-β1/Smad3 pathway-mediated autophagy
por: Ren, Yu, et al.
Publicado: (2023)

Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis
por: Amrute, Junedh M., et al.
Publicado: (2023)

Central role of cardiac fibroblasts in myocardial fibrosis of diabetic cardiomyopathy
por: Cheng, Yanan, et al.
Publicado: (2023)

Myocardial Fibrosis in Hypertrophic Cardiomyopathy: A Perspective from Fibroblasts
por: Schlittler, Maja, et al.
Publicado: (2023)

Radiolabeled fibroblast activation protein inhibitors in the evaluation of myocardial fibrosis
por: Su, Xiangyu, et al.
Publicado: (2023)

SMOC2 inhibits calcification of osteoprogenitor and endothelial cells
por: Peeters, Tine, et al.
Publicado: (2018)

SMOC approach for total knee arthroplasty in valgus knees
por: Li, Tao, et al.
Publicado: (2022)

BMP‐Smad Signaling Regulates Postnatal Crown Dentinogenesis in Mouse Molar
por: Omi, Maiko, et al.
Publicado: (2019)

Mechanisms of Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models
por: Umbarkar, Prachi, et al.
Publicado: (2021)

Xinfuli Granule improves post-myocardial infarction ventricular remodeling and myocardial fibrosis in rats by regulating TGF-β/Smads signaling pathway
por: Ma, Jie, et al.
Publicado: (2017)

Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway
por: Tan, Zhuojing, et al.
Publicado: (2022)

Matrix metalloproteinase 3 regulates angiotensin II-induced myocardial fibrosis cell viability, migration and apoptosis
por: Shu, Jin, et al.
Publicado: (2021)

Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways
por: Yao, Lixia, et al.
Publicado: (2021)

Spatio-Temporal Distribution of Smads and Role of Smads/TGF-β/BMP-4 in the Regulation of Mouse Bladder Organogenesis
por: Islam, Syed S., et al.
Publicado: (2013)

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway
por: Wang, Yinhui, et al.
Publicado: (2021)

BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 signaling pathway
por: Guo, Jingdong, et al.
Publicado: (2017)

Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction
por: Zhu, Fuli, et al.
Publicado: (2013)

Effects of Direct Renin Inhibition on Myocardial Fibrosis and Cardiac Fibroblast Function
por: Zhi, Hui, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dr7elnia1b8e583aq5fg871lno