Cargando…

High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most lethal and malignant types of cancer that affects global human health. The present study aimed to investigate the effect of pyruvate kinase muscle isozyme M2 (PKM2) expression on the clinical features and prognosis of HCC. The present study employed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Dong-Hui, Lv, Wen-Wen, Li, Wen-Xing, Gao, Yue-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096177/ https://www.ncbi.nlm.nih.gov/pubmed/30127967 http://dx.doi.org/10.3892/ol.2018.9100

Ejemplares similares

Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery
por: Lv, Wen-Wen, et al.
Publicado: (2018)

Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma
por: Chen, Zhiao, et al.
Publicado: (2014)

Tumor-infiltrating immune cells in hepatocellular carcinoma: Tregs is correlated with poor overall survival
por: Yu, SiZhe, et al.
Publicado: (2020)

A Novel Nomogram Model to Predict the Recurrence-Free Survival and Overall Survival of Hepatocellular Carcinoma
por: Zhang, Shu-Wen, et al.
Publicado: (2022)

Transforming growth factor-β and peripheral regulatory cells are negatively correlated with the overall survival of hepatocellular carcinoma
por: An, Yang, et al.
Publicado: (2018)

Haptoglobin expression correlates with tumor differentiation and five-year overall survival rate in hepatocellular carcinoma
por: Tai, Chun-San, et al.
Publicado: (2017)

Decreased expression of COLEC10 predicts poor overall survival in patients with hepatocellular carcinoma
por: Zhang, Baozhu, et al.
Publicado: (2018)

Decreased Expression of NUSAP1 Predicts Poor Overall Survival in Cervical Cancer
por: Xie, Qiqi, et al.
Publicado: (2020)

PKM2 regulates Gli1 expression in hepatocellular carcinoma
por: XU, QIURAN, et al.
Publicado: (2014)

Albumin-to-Alkaline Phosphatase Ratio as an Independent Prognostic Factor for Overall Survival of Advanced Hepatocellular Carcinoma Patients without Receiving Standard Anti-Cancer Therapies
por: Cai, Xiurong, et al.
Publicado: (2018)

PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive Microenvironment
por: Li, Tian-En, et al.
Publicado: (2020)

Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients
por: Li, Wei, et al.
Publicado: (2017)

Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma
por: Liu, Gao-Min, et al.
Publicado: (2019)

Decreased CDKL2 Expression in Clear Cell Renal Cell Carcinoma Predicts Worse Overall Survival
por: Chen, Zhan, et al.
Publicado: (2022)

IDO and intra‐tumoral neutrophils were independent prognostic factors for overall survival for hepatocellular carcinoma
por: Wang, Yan, et al.
Publicado: (2019)

The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose
por: Li, Xiang, et al.
Publicado: (2018)

Potential microRNA panel for the diagnosis and prediction of overall survival of hepatocellular carcinoma with hepatitis B virus infection
por: Zhang, Qi, et al.
Publicado: (2020)

A sample model established by S-index predicting overall survival after curative resection of primary hepatocellular carcinoma
por: Chen, Lei, et al.
Publicado: (2019)

CENPE expression is associated with its DNA methylation status in esophageal adenocarcinoma and independently predicts unfavorable overall survival
por: Zhu, Xueqiang, et al.
Publicado: (2019)

A cancer stem cell associated gene signature for predicting overall survival of hepatocellular carcinoma
por: Liang, Xin-Yi, et al.
Publicado: (2022)

Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma
por: Liu, Yan, et al.
Publicado: (2017)

Fibrinogen-to-albumin ratio predicts overall survival of hepatocellular carcinoma
por: Sun, Hao, et al.
Publicado: (2023)

Identification of a five-gene signature in association with overall survival for hepatocellular carcinoma
por: Yang, Lei, et al.
Publicado: (2021)

Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
por: Dayton, Talya L., et al.
Publicado: (2016)

Survivin expression as an independent predictor of overall survival in malignant peritoneal mesothelioma
por: Zhang, Guozun, et al.
Publicado: (2020)

Significant predictors of overall survival in patients with hepatocellular carcinoma after surgical resection
por: Lin, Chih-Wen, et al.
Publicado: (2018)

Decreased expression of Sushi Domain Containing 2 correlates to progressive features in patients with hepatocellular carcinoma
por: Liu, Xin-rui, et al.
Publicado: (2016)

Identification of ferroptosis-related genes for overall survival prediction in hepatocellular carcinoma
por: Luo, Lianxiang, et al.
Publicado: (2022)

Identification and Validation of a Four-Gene Ferroptosis Signature for Predicting Overall Survival of Lung Squamous Cell Carcinoma
por: Wang, Qi, et al.
Publicado: (2022)

Model to Predict Overall Survival in Patients With Hepatocellular Carcinoma After Curative Hepatectomy
por: Zhang, Li-xiang, et al.
Publicado: (2021)

LINE-1 hypomethylation in human hepatocellular carcinomas correlates with shorter overall survival and CIMP phenotype
por: Anwar, Sumadi Lukman, et al.
Publicado: (2019)

GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism()
por: Zhou, Qiang, et al.
Publicado: (2022)

PKM2 and cancer: The function of PKM2 beyond glycolysis
por: DONG, GAOCHAO, et al.
Publicado: (2016)

Decreased Cytoplasmic Expression of ADAMTS14 Is Correlated with Reduced Survival Rates in Oral Squamous Cell Carcinoma Patients
por: Lin, Yueh-Min, et al.
Publicado: (2020)

Low APOA-1 Expression in Hepatocellular Carcinoma Patients Is Associated With DNA Methylation and Poor Overall Survival
por: Guo, Yingyun, et al.
Publicado: (2021)

USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination-mediated degradation
por: Lv, Tao, et al.
Publicado: (2023)

Body Composition Features Predict Overall Survival in Patients With Hepatocellular Carcinoma
por: Singal, Amit G, et al.
Publicado: (2016)

Establishment and Validation of an MTORC1 Signaling-Related Gene Signature to Predict Overall Survival in Patients with Hepatocellular Carcinoma
por: Yao, Zheng, et al.
Publicado: (2021)

PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
por: Feng, Jiao, et al.
Publicado: (2019)

Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2
por: Liu, Tong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e7c0onolmqtecjkerpj1s03em8