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Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress

Poor prognosis and chemotherapy tolerance are the main obstacles encountered in the treatment of cholangiocarcinoma. Chloroquine (CQ), an antimalarial agent, is able to induce sustained endoplasmic reticulum (ER) stress by functioning as an autophagy inhibitor. The present study indicated that CQ ha...

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Detalles Bibliográficos
Autores principales:	Jia, Baoxing, Xue, Yanan, Yan, Xiaoyu, Li, Jiuling, Wu, Yao, Guo, Rui, Zhang, Juanjuan, Zhang, Lichao, Li, Yaping, Liu, Yahui, Sun, Liankun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096195/ https://www.ncbi.nlm.nih.gov/pubmed/30127955 http://dx.doi.org/10.3892/ol.2018.9131

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