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Expression of V-domain immunoglobulin suppressor of T cell activation is associated with the advanced stage and presence of lymph node metastasis in ovarian cancer

V-domain immunoglobulin suppressor of T cell activation (VISTA) is a novel negative immune checkpoint that belongs to the B7 family. VISTA is primarily expressed on hematopoietic cells and inhibits T cell proliferation and cytokine production. The blockade of VISTA has demonstrated promising results...

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Detalles Bibliográficos
Autores principales: Liao, Hong, Zhu, Hongmei, Liu, Shanling, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096210/
https://www.ncbi.nlm.nih.gov/pubmed/30127950
http://dx.doi.org/10.3892/ol.2018.9059