Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry

Neuroblastoma is one of the most commonly found solid tumors in children. The monoclonal antibody dinutuximab (DNX) targets the sialic acid-containing glycosphingolipid GD2 expressed on almost all neuroblastoma tumor cells and induces cell lysis. However, the expression of GD2 is not limited to tumo...

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Detalles Bibliográficos
Autores principales: El Amrani, Mohsin, Szanto, Celina L., Hack, C. Erik, Huitema, Alwin D. R., Nierkens, Stefan, van Maarseveen, Erik M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096702/
https://www.ncbi.nlm.nih.gov/pubmed/29938370
http://dx.doi.org/10.1007/s00216-018-1198-0

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