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Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease

The herpes simplex virus 1 (HSV-1) virion host shutoff (vhs) protein is an endoribonuclease that binds to the cellular translation initiation machinery and degrades associated mRNAs, resulting in the shutoff of host protein synthesis. Hence, its unrestrained activity is considered lethal, and it has...

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Detalles Bibliográficos
Autores principales:	Elliott, Gillian, Pheasant, Kathleen, Ebert-Keel, Katja, Stylianou, Julianna, Franklyn, Ashley, Jones, Juliet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096803/ https://www.ncbi.nlm.nih.gov/pubmed/29925667 http://dx.doi.org/10.1128/JVI.00818-18

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