HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes

We have previously shown that HIV-1-infected children develop broader and more potent neutralizing antibody responses than adults. This study aimed to determine the antibody specificities in 16 HIV-1 subtype C-infected children who displayed exceptional neutralization breadth on a 22-multisubtype vi...

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Detalles Bibliográficos
Autores principales: Ditse, Zanele, Muenchhoff, Maximilian, Adland, Emily, Jooste, Pieter, Goulder, Philip, Moore, Penny L., Morris, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096808/
https://www.ncbi.nlm.nih.gov/pubmed/29950423
http://dx.doi.org/10.1128/JVI.00878-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096808/
https://www.ncbi.nlm.nih.gov/pubmed/29950423
http://dx.doi.org/10.1128/JVI.00878-18

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