Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich’s ataxia patients

Transcriptional changes in Friedreich’s ataxia (FRDA), a rare and debilitating recessive Mendelian neurodegenerative disorder, have been studied in affected but inaccessible tissues—such as dorsal root ganglia, sensory neurons and cerebellum—in animal models or small patient series. However, transcr...

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Detalles Bibliográficos
Autores principales: Nachun, Daniel, Gao, Fuying, Isaacs, Charles, Strawser, Cassandra, Yang, Zhongan, Dokuru, Deepika, Van Berlo, Victoria, Sears, Renee, Farmer, Jennifer, Perlman, Susan, Lynch, David R, Coppola, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097013/
https://www.ncbi.nlm.nih.gov/pubmed/29790959
http://dx.doi.org/10.1093/hmg/ddy198

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