Cargando…
Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains
This study is concerned with identifying features of 4-aminoquinoline scaffolds that can help pinpoint characteristics that enhance activity against chloroquine-resistant parasites. Statistically valid predictive models are reported for a series of 4-aminoquinoline analogues that are active against...
Autores principales: | Lawrenson, Alexandre S., Cooper, David L., O’Neill, Paul M., Berry, Neil G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097041/ https://www.ncbi.nlm.nih.gov/pubmed/30120591 http://dx.doi.org/10.1007/s00894-018-3755-z |
Ejemplares similares
-
Antimalarial Activity and Mechanisms of Action of Two Novel 4-Aminoquinolines against Chloroquine-Resistant Parasites
por: Aguiar, Anna Caroline Campos, et al.
Publicado: (2012) -
Synthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparum
por: Rajapakse, Chandima S. K., et al.
Publicado: (2015) -
Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
por: Sahraei, Zahra, et al.
Publicado: (2020) -
Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia
por: Mekonnen, Seleshi Kebede, et al.
Publicado: (2014) -
Dual-functioning antimalarials that inhibit the chloroquine-resistance transporter
por: Egan, Timothy J, et al.
Publicado: (2013)